Samelyuk Y.G., Kaplaushenko A.G., Avramenko A.I., Pryakhin O.R.. The Study Of Acid-base Properties Of 5-(4-methoxyphenyl, 3,4,5-trimethoxyphenyl)-1,2,4-triazole-3-thioacetic Acids And Their Salts

Natural Sciences / Chemistry / Pharmacy

Submitted on: Oct 11, 2013, 07:59:23

Description: New S-derivatives of 1,2,4-triazole have been synthesized, namely 2-(5-(4-methoxyphenyl-(3,4,5-trimethoxyphenyl))-1,2,4-triazole-3-ylthio)acetic acids. Theoretical and practical determination of ionization constants of some 2-(4-R-4H-1,2,4-triazole-3-ilthio)acetic acids and its salts have been set. Following the discussion, the influence of the presence and nature of substituents at C5 atom in 1,2,4-triazole nucleus on acidity and basicity of compounds has been set.

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