Parshikov I.A.. Microbial Transformation of Some Ethylpyridines by Fungi
Submitted on: Jan 25, 2022, 11:14:44
Natural Sciences / Chemistry / Medicinal chemistry
Description: We were observed transformation 4-ethylpyridine and 2-methyl-5-ethylpyridine by fungus Beauveria bassiana ATCC 7159. Stereoselective oxidation of methylene group leading to the optically active (-)-(1-hydroxyethyl)pyridine was shown. Besides, the hydroxylation of methyl groups and the oxidation of the heterocyclic ring in the nitrogen atom to the respective primary alcohols and N-oxides were observed. Keywords: transformation, 4-ethylpyridine, 2-methyl-5-ethylpyridine
The Library of Congress (USA) reference page : http://lccn.loc.gov/cn2013300046.
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